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2015| September-December | Volume 21 | Issue 3
Online since
September 9, 2015
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ORIGINAL ARTICLES
Sexual functioning in men living with a spinal cord injury–A narrative literature review
MM Sunilkumar, Patricia Boston, MR Rajagopal
September-December 2015, 21(3):274-281
DOI
:10.4103/0973-1075.164886
PMID
:26600694
Background:
Sexual dysfunction is a major concern for Indian men living with a spinal cord injury
Objectives:
To examine the literature related to sexuality traumatic cord injury and its impact on sexual functioning.
Materials and Methods:
Databases using Cumulative Index to Nursing and Allied Health Literature (CINAHL) 2000–2012, Medline 1989–2012, Applied Social Sciences Index and Abstracts (ASSIA) 1989–2012 and Google Scholar were the search engines used used for literature review.
Results:
The search yielded a total of 457 articles and only 75 of them were found relevant. The minimum number of articles required to meet the inclusion criteria for this review was 25–30 articles. Out of the 75 articles, 33 were considered relevant or related to the topic of sexual functioning, spinal cord injury, and paraplegia. Six areas were identified: Sexual stigmatization, physiological barriers to sexual satisfaction, clinical aspects of sexual functioning, biomedical approaches to sexual dysfunction, partner satisfaction, and lack of accessibility to sexual education.
Conclusion:
Spinal cord injury and sexual functioning affects a large segment of the male Indian population, yet most current research focuses on quantitative measurement with the emphasis on ejaculatory dysfunction, orgasm impairment, incontinence, and other physiological dysfunction. Further research is needed to address the subjective accounts of patients themselves with respect to the emotional and social impact of sexual disability. This would help to identify the best possible outcomes for both treatment and rehabilitation.
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REVIEW ARTICLE
Constitutional and legal protection for life support limitation in India
RK Mani
September-December 2015, 21(3):258-261
DOI
:10.4103/0973-1075.164903
PMID
:26600691
Appropriate treatment limitations towards the end of life to reduce unwanted burdens require ethical clarity that is supported by appropriate legislation. The lack of knowledge of enabling legal provisions, physicians feel vulnerable to legal misinterpretation of treatment limiting decisions. In India the lack of societal awareness, inadequate exploration of the gray areas of bio-ethics and unambiguous legal position relating to terminal illness have resulted in poor quality end of life care. Much of the perceived vulnerability by the physician is attributable to insufficient knowledge and understanding of existing constitutional and legal position in India. While we await informed legal and legislative opinion, this paper highlights possible legal liabilities arising from treatment limitation decisions with available defense. It is hoped that such clarity would lead to more confident ethical decisions and improved end of life care for patients.
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ORIGINAL ARTICLES
Screening of psychological distress in cancer patients during chemotherapy: A cross-sectional study
Raja Paramjeet Banipal Singh, Harminder Singh, Chiranjeev Jhajj Singh, Kanwardeep Tiwana Kaur
September-December 2015, 21(3):305-310
DOI
:10.4103/0973-1075.164887
PMID
:26600699
Objective:
The objective of this prospective, noninterventional, 8-months, observational study was to analyze and compare depression, anxiety, and stress (DAS) levels and their impacting factors in homogenous surviving cancer patients receiving chemotherapy as compared to normal control.
Materials and Methods:
A prospective and descriptive study was carried out jointly by Pharmacology and Oncology departments of a tertiary care center in Malwa region of Punjab. The data was collected by administering the validated questionnaire/response (21-item Depression Anxiety and Stress Scale (DASS-21)) after taking ethical approval and informed consent.
Results:
All eligible 300 subjects participated in the study and they were compared with 300 matched control. The mean age of the cases (cancer patients) and controls was 50.58 ± 13.64 and 46.1 ± 11.78 (mean (M) ± standard deviation (SD)) years. Statistical significant difference was observed in mean 'scoring of DAS' in cancer patients when compared with control groups. Anxiety mean scoring showed a statistical significant difference in groups (according to chemotherapy cycles given and duration of disease). Stress was more observed in breast cancer patients.
Conclusion:
Holistic approach in cancer management including psychological evaluation and its solution at appropriate time/stage signifies the need of time as the present study revealed that the percentage of DAS as per the DASS scale was 90, 56, and 28%, respectively. A judicious diagnosis with an apposite intercession including psychological consultation with social support at appropriate time may alleviate the extra burden of psychological disorder, rather enhance the quality of life of cancer-affected rural population.
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Association of coping styles with quality of life in cancer patients
Jalal Shakeri, Mohamad Kamangar, Ehteram Ebrahimi, Mozafar Aznab, Hania Shakeri, Farid Arman
September-December 2015, 21(3):298-304
DOI
:10.4103/0973-1075.164890
PMID
:26600698
Backgrounds and Aim:
Cancer patients experience a high level of stress caused by the disease and treatment processes. Dealing with cancer using more beneficial coping styles can effectively improve the quality of life (QOL) and reduce the side effects of cancer, and it is treatment. In this study, we aimed to investigate the relationship between coping styles and QOL in cancer patients.
Methods:
The study was performed on 150 cancer patients (71 females and 79 males) admitted to the hospitals affiliated with Kermanshah University of Medical Sciences. Endler and Parker Coping Inventory for Stressful Situations, and World Health Organization's Quality of Life Questionnaire were used to evaluate their coping style and QOL, respectively.
Results:
The Present study showed in cancer patients being male, single, having higher salary and education, and lower age are related to higher QOL. Furthermore, in general, QOL of cancer patients was positively correlated with avoidant coping style (
P
< 0.05,
r
: 0.170) and negatively associated with emotion-focused coping styles (
P
< 0.01,
r
: −0.378).
Conclusion:
The results suggested that focusing on a patient's coping style, predominantly on an emotion-focused coping style, is essential to improve patient's QOL, and that patients possibly to employ a more emotion-oriented coping style should receive enough notice, particularly before discharge.
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A randomized controlled trial evaluating the role of honey in reducing pain due to radiation induced mucositis in head and neck cancer patients
Saurabh Samdariya, Shirley Lewis, Heena Kauser, Iqbal Ahmed, Dewesh Kumar
September-December 2015, 21(3):268-273
DOI
:10.4103/0973-1075.164892
PMID
:26600693
Background:
There are various drugs tried for relieving pain associated with radiation-induced mucositis. This paper aims to study role of honey in relieving pain due to radiation induced mucositis in head and neck cancer patients receiving concomitant chemoradiation.
Materials and Methods:
A randomized controlled trial on 78 subjects (40 in test group and 38 in control group) was undertaken to study the analgesic effect of honey, but the analysis of 69 patients was done as nine patients (four in test and five in control group) were lost to follow-up or left treatment in between the study. All patients were advised to do salt-soda and benzydamine mouth gargles, alternatively every 3 hours. Test group patients additionally received 20 ml honey three times a day during the entire course of radiation treatment and 3 months following radiation therapy (RT).
Results:
Honey significantly reduced the severity of mucositis associated pain and resulted in lesser treatment gaps and a decrease in overall radiotherapy treatment duration. None of the test group and majority of controls (51.5%) had severe pain score during the 7
th
week of RT. The same pattern was seen in the post-RT period. Mean pain score was significantly different in both groups during all weeks during and upto 6 weeks post-RT (mean score of 3.08 and 6.54 for test and control respectively at 7
th
week RT,
P
< 0.001).
Conclusion:
Honey being a cheap, palatable, and natural medicament can be used for decreasing pain associated with radiation-induced mucositis in cancer patients.
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The prevalence and characteristics of pain in critically ill cancer patients: A prospective nonrandomized observational study
Mayank Gupta, Malvinder Singh Sahi, AK Bhargava, Vineet Talwar
September-December 2015, 21(3):262-267
DOI
:10.4103/0973-1075.164894
PMID
:26600692
Context:
Pain is a distressing symptom common to all stages and ubiquitous at all levels of care in cancer patients. However, there is a lack of scientific literature on prevalence, severity, predictors, and the quality of pain in cancer patients admitted to an Intensive Care Unit (ICU).
Objectives:
To elucidate the prevalence of pain, moderate to severe pain, neuropathic pain, chronic pain, and pain as the most distressing symptom in critically ill-cancer patients at the time of ICU admission.
Methods:
We prospectively interviewed 126 patients within first 24 h of admission to a medical ICU. The patients were assessed for the presence of pain, its severity, sites, duration, nature, and its impact as a distressing symptom. Numerical Rating Scale and self-report version of Leeds Assessment of Neuropathic Signs and Symptoms were used to elucidate intensity of pain and neuropathic pain, respectively. Demographic characteristics such as age and sex, primary site, and stage of cancer were considered for a possible correlation with the prevalence of pain.
Results:
Of 126 patients included in the study 95 (75.40%), 79 (62.70%), 34 (26.98%), and 17 (13.49%) patients had pain, moderate-severe, chronic, and neuropathic pain, respectively. The average duration of pain was 171.16 ± 716.50 days. Totally, 58 (46.03%) and 42 (42.01%) patients had at least one and more than equal to 2 neuropathic pain symptoms, respectively. The primary malignancies associated with the highest prevalence of pain were genitourinary, hematological, and head and neck whereas breast and lung cancers were associated with the highest prevalence of neuropathic and chronic pain, respectively.
Conclusion:
The prevalence of pain among critically ill-cancer patients is high. Assessment for pain at the time of ICU admission would ensure appropriate assessment for the presence, type, severity, and the significance imparted to it.
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Practice of Iranian adolescents with hemophilia in prevention of complications of hemophilia
Leila Valizadeh, Fahimeh Alsadat Hosseini, Vahid Zamanzadeh, Fatemeh Heidarnezhad, Madineh Jasemi, Kamran Bagheri Lankarani
September-December 2015, 21(3):328-337
DOI
:10.4103/0973-1075.164895
PMID
:26600702
Background:
Prerequisite for management of a chronic disease involves knowledge about its complications and their prevention. Hemophilia in adolescents influences all the aspects of their lives and thier performance.
Objectives:
The present study aimed to determine the performance of Iranian hemophilic adolescents in prevention of disease complications.
Patients and Methods:
In this descriptive-analytical study, 108 adolescents with hemophilia were selected through convenience sampling. Their performance in preventing the complications of hemophilia was evaluated by sending a semi-structured questionnaire to their addresses throughout Iran. Then, the data was analysed using the Statistical Package for Social Sciences (SPSS) software (v. 13) and descriptive and interferential statistics were used.
Results:
Overall, 32.1% of the participants controlled bleeding during the 1
st
hour. Inaccessibility of coagulation products was mainly responsible for inhibiting timely and proper bleeding control. In order to relieve bleeding associated pain, only 39.0% of the adolescents used analgesics. On the other hand, 19.8% of the subjects used nonpharmacological methods to relieve pain. The majority of the adolescents did not participate in sport activities (65.4%) others allocated less than 5 hours a week to physical activities (70.5%). In addition, the participants did not have favorable dietary patterns, exercise habits, and dental care. The results showed a significant relationship between the adolescents' preventive practice with coagulation disorders and utilization of pharmacological pain relief methods. Also, significant relationships were found between severity of the disease; participating in physical activities, number of hours of physical activities; and disease complications.
Conclusions:
Iranian adolescents did not exhibit favorable practices towards complication prevention.
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Symptoms experienced by cancer patients and barriers to symptom management
Malathi G Nayak, Anice George, MS Vidyasagar, Stanley Mathew, Sudhakar Nayak, Baby S Nayak, YN Shashidhara, Asha Kamath
September-December 2015, 21(3):349-354
DOI
:10.4103/0973-1075.164893
PMID
:26600705
Background:
People living with cancer experience wide variety of symptoms. If symptoms are not managed well, it may hamper an individual's ability to continue his or her activities of daily life. Treatment of symptoms relieves suffering and improves the rate of recovery as well as the quality of life.
Objectives:
To assess the symptoms of suffering among cancer patients and to identify the perceived barriers to their symptom management.
Materials and Methods:
A cross-sectional study was carried out among 768 cancer patients selected by stratified sampling with a proportionate selection from each stratum. Data were collected from cancer patients by interview technique using structured validated questionnaire.
Results:
Majority of the samples (30.2%) belonged to the age group of 51–60 years, most of them were diagnosed with head and neck cancer (40.1%) and 57.7% had stage III disease. The majority of the patients studied had pain (77%), tiredness (96.5%), disturbed sleep (96.4%), weight loss (63.3%), and irritability (85.7%). Most of the patients had lack of appetite (89.4%), feeling of sadness (96.6%), worry (94.5%), and feeling of nervousness (82.8%). Majority of the patients had some misconception regarding symptoms, that is, increasing pain signifies disease progression (92.7%), medicine to control pain may weaken the immune system (89.9%) and pain is inevitable for cancer patients (78.5%). Seventy-seven percent of samples reported that the anxiety or depression is expected after the diagnosis of cancer.
Conclusion:
This study provides an overview of symptoms among cancer patients and barriers experienced by them.
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Validation of the euroqol five-dimensions - three-level quality of life instrument in a classical Indian language (Odia) and its use to assess quality of life and health status of cancer patients in Eastern India
Swagata Tripathy, Upendra Hansda, Newfight Seth, Satyajit Rath, PB Rao, TS Mishra, SH Subba, Rekha Das, Sukdev Nayak, Nilamadhab Kar
September-December 2015, 21(3):282-288
DOI
:10.4103/0973-1075.164896
PMID
:26600695
Background and Objectives:
The EuroQol five-dimensions – 3-level (EQ5D) is a versatile quality of life (QOL) instrument with five dimensions (mobility, self-care, usual activities, pain/discomfort, and anxiety/depression) and a visual analog scale. It can be used to calculate quality-adjusted life years. We aimed to evaluate the validity, reliability, and responsiveness of an Odia version of EQ5D and to study the QOL of cancer patients in our part of the country as cancer treatment in India still focuses largely on longevity due to scarcity of resources.
Materials and Methods:
The EQ5D tool was translated into Odia language in collaboration with the EQ group. This tool and the World Health Organization-5 (WHO-5) questionnaires were administered to 155 surgical outpatients and 150 cancer patients in two hospitals of Eastern India. The convergent and discriminant validities (construct validity), concurrent validity, reliability (test-retest method of administering the tool to a part of the population after 7–14 days), and the internal consistency (Cronbach's alpha) were measured using preestablished hypotheses. The data from the cancer patients were analyzed separately.
Results:
The QOL worsened with age and was worse in cancer patients proved that the tool had good construct validity. The Anxiety Depression dimension had good correlation with all the dimensions WHO-5 (rho > 0.4) indicating a good concurrent validity. Internal consistency and reliability of the tool were good (Cronbach's alpha > 0.7). Cancer patients had a poor QOL (mean EQ5D index 0.37SD 0.4) with male patients, patients with Grade II cancer or referred for pain care services and those with living spouses reporting worse QOL.
Conclusions:
The Odia version of the EQ5D has good reliability and validity for the measurement of health status in cancer and outpatient department patients. Cancer patients in this part of the country have a poor QOL and may need a closer look at pain management and improved societal support systems.
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Role of communication for pediatric cancer patients and their family
Rajesh Kumar Singh, Aditya Raj, Sujata Paschal, Shahab Hussain
September-December 2015, 21(3):338-340
DOI
:10.4103/0973-1075.164888
PMID
:26600703
Background:
Communication is a key component in medical practice. The area of pediatric palliative care is emotionally distressing for families and healthcare providers. Inadequate communication can increase the stress and lead to mistrust or miscommunication.
Materials and Methods:
Reviewing the literature on communication between physicians, patients, and their family; we identified several barriers to communication such as paternalism in medicine, inadequate training in communication skills, knowledge of the grieving process, special issues related to care of children, and cultural barriers. In order to fill the gap in area of cultural communication, a study questionnaire was administered to consecutive families of children receiving chemotherapy at a large, north Indian referral hospital to elicit parental views on communication.
Results:
Most parents had a protective attitude and favored collusion; however, appreciated truthfulness in prognostication and counseling by physicians; though parents expressed dissatisfaction on timing and lack of prior information by counseling team.
Conclusion:
Training programs in communication skills should teach doctors how to elicit patients' preferences for information. Systematic training programs with feedback can decrease physicians stress and burnout. More research for understanding a culturally appropriate communication framework is needed.
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Perspective of patients, patients' families, and healthcare providers towards designing and delivering hospice care services in a middle income Country
Saber Azami-Aghdash, Morteza Ghojazadeh, Mir Hossein Aghaei, Mohammad Naghavi-Behzad, Zoleikha Asgarlo
September-December 2015, 21(3):341-348
DOI
:10.4103/0973-1075.164898
PMID
:26600704
Introduction:
In view of the recent surge in chronic disease rates and elderly population in the developing countries, there is an urgent felt need for palliative and hospice care services. The present study investigates the views and attitudes of patients and their families, physicians, nurses, healthcare administrators, and insurers regarding designing and delivering hospice care service in a middle income country.
Materials and Methods:
In this qualitative study, the required data was collected using semi structured interviews and was analyzed using thematic analysis. Totally 65 participants from hospitals and Tabriz University of Medical Sciences were selected purposively to achieve data saturation.
Results:
Analyzing the data, five main themes (barriers, facilitators, strategies, attitudes, and service provider) were extracted. Barriers included financial issues, cultural-religious beliefs, patient and family-related obstacles, and barriers related to healthcare system. Facilitators included family-related issues, cultural-religious beliefs, as well as facilitators associated with patients, healthcare status, and benefits of hospice service. Most participants (79%) had positive attitude towards hospice care service. Participant suggested 10 ways to design and deliver effective and efficient hospice care service. They thought the presence of physicians, nurses, and psychologists and other specialists and clergy were necessary in the hospice care team.
Conclusion:
Due to lack of experience in hospice care in developing countries, research for identifying probable barriers and appropriate management for reducing unsuccessfulness in designing and delivering hospice care service seems necessary. Input from the facilitators and their suggested solutions can be useful in planning the policy for hospice care system.
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Nutritional assessment of patients with head and neck cancer in North-East India and dietary intervention
Abhinandan Bhattacharjee, Iqbal Bahar, Abijit Saikia
September-December 2015, 21(3):289-295
DOI
:10.4103/0973-1075.164889
PMID
:26600696
Introduction:
Head and neck cancer (HNCA) patients have poor nutritional status which clearly bears a negative prognosis in cancer. There is no study and consensus on nutritional assessment tools and diet structure for such patients. This study intends to determine the prevalence of malnutrition and formulate a diet chart keeping in view the general food habit and economic condition of HNCA patients of North East (NE) region.
Aim:
To find out an affordable dietary intervention for HNCA patients based on dietary principles. To assess the role of nutritional assessment tools in these group of patients.
Materials and Methods:
This is a 1-year prospective interventional study on HNCA patients attending the Dept of ENT of a teaching hospital. The outcome of the nutritional intervention using a specific diet were assessed using clinical, laboratory and anthropomorphic assessment tools and indices like Prognostic Nutritional Index (PNI) and Nutritional Assessment Index (NAI).
Results:
The study diet provided appropriate amounts of nutrients to HNCA patients as evident from improvements in anthropomorphic parameters and nutritional indices. Clinically, Hemoglobin percentage (Hb%), Body Mass Index (BMI), Mid Arm Circumference (MAC) and triceps skin fold thickness (TST) were found to be reliable malnutrition markers.
Conclusion:
Nutritional Assessment Index has been found to be the best index to evaluate malnutrition. The daily requirement of nutrients for HNCA patients can be satisfactorily met by adopting specific diet chart presented in our study. As no structured diet plan are available in literature, our diet chart can act as a template diet appropriate for HNCA patients of this region.
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Assessment of a hospital palliative care unit (HPCU) for cancer patients; A conceptual framework
Mohammad Reza Rouhollahi, Masoud Saghafinia, Kazem Zandehdel, Ali Ghanbari Motlagh, Ali Kazemian, Mohammad Ali Mohagheghi, Mamak Tahmasebi
September-December 2015, 21(3):317-327
DOI
:10.4103/0973-1075.164901
PMID
:26600701
Introduction:
The first hospital palliative care unit (HPCU) in Iran (FARS-HPCU) has been established in 2008 in the Cancer Institute, which is the largest referral cancer center in the country. We attempted to assess the performance of the HPCU based on a comprehensive conceptual framework. The main aim of this study was to develop a conceptual framework for assessment of the HPCU performances through designing a value chain in line with the goals and the main processes (core and support).
Materials and Methods:
We collected data from a variety of sources, including international guidelines, international best practices, and expert opinions in the country and compared them with national policies and priorities. We also took into consideration the trend of the HPCU development in the Cancer Institute of Iran. Through benchmarking the gap area with the performance standards, some recommendations for better outcome are proposed.
Results:
The framework for performance assessment consisted of 154 process indicators (PIs), based on which the main stakeholders of the HPCU (including staff, patients, and families) offered their scoring. The outcome revealed the state of the processes as well as the gaps. Conclusion: Despite a significant improvement in many processes and indicators, more development in the comprehensive and integrative aspects of FARS-HPCU performance is required. Consideration of all supportive and palliative requirements of the patients through interdisciplinary and collaborative approaches is recommended.
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EDITORIAL
Specialist palliative medicine training in India
Naveen Salins
September-December 2015, 21(3):257-257
DOI
:10.4103/0973-1075.164904
PMID
:26600690
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CASE REPORT
Pain relief can be painful
Ashish Bindra, Parmod Bithal, Navdeep Sokhal, Ankit Arora
September-December 2015, 21(3):355-357
DOI
:10.4103/0973-1075.164913
PMID
:26600706
Mandibular nerve block is periodically used procedure used to treat neuralgic pain in the distribution of trigeminal nerve. It is a commonly performed block in outpatient settings at our institute. We present a case of an elderly edentulous patient with trigeminal neuralgia who suffered recurrent temporomandibular joint (TMJ) dislocation following mandibular nerve block. The patient presented with complaints of severe pain, inability to close mouth, and eat food since 2 days. Anterior closed reduction of TMJ resulted in reduction of joint and immediate pain relief. However, the maneuver failed due to recurrent dislocation of the joint. A Barton dressing was applied to prevent another dislocation. This was followed by autologous blood injection into the joint. This case focuses on the preponderance of clinical evaluation and accentuates the need for additional forethought to be taken during pain procedures, particularly in the geriatric population.
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ORIGINAL ARTICLES
Is Karnofsky performance status correlate with better overall survival in palliative conformal whole brain radiotherapy? Our experience
Alessia Reali, Simona Allis, Andrea Girardi, Roberta Verna, Lavinia Bianco, Maria Grazia Ruo Redda
September-December 2015, 21(3):311-316
DOI
:10.4103/0973-1075.164891
PMID
:26600700
Aim:
Brain metastases (BMs) are a common event in the progression of many human cancers. The aim of this study was to evaluate the potential prognostic factors for the clinical identification of a subgroup of patients that could benefit from whole brain conformal radiotherapy (WBRT).
Materials and Methods:
From January 2010 to February 2014, 80 patients with a diagnosis of BMs underwent WBRT at our Radiation Oncology Department, San Luigi Hospital, Italy. Among them, 36 medical records were retrospective reviewed. Gender, age, Karnofsky performance status (KPS), number of BMs on computed tomography and/or magnetic resonance images, presence or absence of perilesional edema, presence or absence of necrosis pattern, and histology of primary tumor were analyzed. Univariate and multivariate analyses were performed.
Results:
In our cohort of patients, significant prognostic factors for 20 months overall survival was KPS> 70, while a statistical trend (
P
= 0.098) was registered regarding primary breast.
Conclusion:
WBRT can be still considered a standard and effective treatment in patients with BMs. High KPS and breast cancer primary tumor seem to be useful parameters for characterize a subgroup of patients with more favorable prognosis.
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81
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LETTERS TO EDITOR
Role of early caudal epidural in epidural metastasis mediated neuropathic cancer pain. Delineating the safety and efficacy measures
Mayank Gupta
September-December 2015, 21(3):359-360
DOI
:10.4103/0973-1075.164899
PMID
:26600708
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1,660
72
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ORIGINAL ARTICLES
Commentary
Sarbani Ghosh Laskar, Abhishek Chatterjee
September-December 2015, 21(3):296-297
DOI
:10.4103/0973-1075.164900
PMID
:26600697
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1,642
59
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LETTERS TO EDITOR
Transnasal approach to sphenopalatine ganglion blockade: An alternate technique
Renuka Pai, Lakshmi Vas
September-December 2015, 21(3):360-361
DOI
:10.4103/0973-1075.164885
PMID
:26600709
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1,628
68
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Searching for the right evidence: India's contribution to the cochrane pain, palliative and supportive care group
Hemanshu Prabhakar, Indu Kapoor, Charu Mahajan
September-December 2015, 21(3):358-359
DOI
:10.4103/0973-1075.164897
PMID
:26600707
[FULL TEXT]
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1,563
67
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