Indian Journal of Palliative Care
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Year : 2009  |  Volume : 15  |  Issue : 2  |  Page : 159--161

Palliative benefits of the multimodality approach in the re-treatment of recurrent malignant glioma: Two case reports

Department of Radiation Oncology, M.S. Ramaiah Medical Teaching Hospital, Bangalore - 560 054, India

Correspondence Address:
T R Arulponni
Department of Radiation Oncology, M.S. Ramaiah Medical Teaching Hospital, Bangalore - 560 054
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1075.58464

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Two young male patients treated seven and four years back, for malignant glioma, returned with recurrence at the same site, with a World Health Organization (WHO) Performance Score of four and two. Both underwent resurgery and received postoperative reirradiation of 5040 cGy in 28 fractions and concurrent Temozolomide 75 mg/m 2 body surface area (BSA) daily, and one patient received additional adjuvant Temozolomide 250 mg (150 mg/m 2 BSA). Both patients tolerated the treatment well with 16 and 14 months follow-up from the time of recurrence. They were symptom-free, with normal physical function and good mental state, and resumed their respective jobs.


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Online since 1st October '05
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