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ORIGINAL ARTICLE
Year : 2017  |  Volume : 23  |  Issue : 3  |  Page : 237--246

Effects of a yoga program on mood states, quality of life, and toxicity in breast cancer patients receiving conventional treatment: A randomized controlled trial

Raghavendra Mohan Rao1, Nagaratna Raghuram2, Hongasandra Ramarao Nagendra3, Gopinath S Kodaganur4, Ramesh S Bilimagga5, HP Shashidhara6, Ravi B Diwakar6, Shekhar Patil6, Nalini Rao5 
1 Department of Complementary and Alternative Medicine, Healthcare Global Enterprises Ltd., Bengaluru, Karnataka, India
2 Department of life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana, Bengaluru, Karnataka, India
3 Department of Research and Development, Swami Vivekananda Yoga Anusandhana Samsthana, Bengaluru, Karnataka, India
4 Department of Surgical Oncology, HCG Bangalore institute of Oncology Specialty Center, Bengaluru, Karnataka, India
5 Department of Radiation Oncology, HCG Bangalore institute of Oncology Specialty Center, Bengaluru, Karnataka, India
6 Department of Medical Oncology, HCG Bangalore institute of Oncology Specialty Center, Bengaluru, Karnataka, India

Correspondence Address:
Nagaratna Raghuram
Department of Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana, No. 19, Eknath Bhavan, Gavipuram Circle, K.G Nagar, Bengaluru  -  560  019, Karnataka
India

Aims: The aim of this study is to compare the effects of yoga program with supportive therapy counseling on mood states, treatment-related symptoms, toxicity, and quality of life in Stage II and III breast cancer patients on conventional treatment. Methods: Ninety-eight Stage II and III breast cancer patients underwent surgery followed by adjuvant radiotherapy (RT) or chemotherapy (CT) or both at a cancer center were randomly assigned to receive yoga (n = 45) and supportive therapy counseling (n = 53) over a 24-week period. Intervention consisted of 60-min yoga sessions, daily while the control group was imparted supportive therapy during their hospital visits. Assessments included state-trait anxiety inventory, Beck's depression inventory, symptom checklist, common toxicity criteria, and functional living index-cancer. Assessments were done at baseline, after surgery, before, during, and after RT and six cycles of CT. Results: Both groups had similar baseline scores. There were 29 dropouts 12 (yoga) and 17 (controls) following surgery. Sixty-nine participants contributed data to the current analysis (33 in yoga, and 36 in controls). An ANCOVA, adjusting for baseline differences, showed a significant decrease for the yoga intervention as compared to the control group during RT ( first result) and CT (second result), in (i) anxiety state by 4.72 and 7.7 points, (ii) depression by 5.74 and 7.25 points, (iii) treatment-related symptoms by 2.34 and 2.97 points, (iv) severity of symptoms by 6.43 and 8.83 points, (v) distress by 7.19 and 13.11 points, and (vi) and improved overall quality of life by 23.9 and 31.2 points as compared to controls. Toxicity was significantly less in the yoga group (P = 0.01) during CT. Conclusion: The results suggest a possible use for yoga as a psychotherapeutic intervention in breast cancer patients undergoing conventional treatment.


How to cite this article:
Rao RM, Raghuram N, Nagendra HR, Kodaganur GS, Bilimagga RS, Shashidhara H P, Diwakar RB, Patil S, Rao N. Effects of a yoga program on mood states, quality of life, and toxicity in breast cancer patients receiving conventional treatment: A randomized controlled trial.Indian J Palliat Care 2017;23:237-246


How to cite this URL:
Rao RM, Raghuram N, Nagendra HR, Kodaganur GS, Bilimagga RS, Shashidhara H P, Diwakar RB, Patil S, Rao N. Effects of a yoga program on mood states, quality of life, and toxicity in breast cancer patients receiving conventional treatment: A randomized controlled trial. Indian J Palliat Care [serial online] 2017 [cited 2020 Apr 7 ];23:237-246
Available from: http://www.jpalliativecare.com/article.asp?issn=0973-1075;year=2017;volume=23;issue=3;spage=237;epage=246;aulast=Rao;type=0