Indian Journal of Palliative Care
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 CASE REPORT
Year : 2018  |  Volume : 24  |  Issue : 3  |  Page : 372--374

Olanzapine in the treatment of refractory nausea and vomiting in palliative care settings


Department of Onco-Anaesthesiology and Palliative Medicine, Dr. BRAIRCH, AIIMS, New Delhi, India

Correspondence Address:
Dr. Nishkarsh Gupta
Room No 139, Department of Onco-Anaesthesiology and Palliative Medicine, Dr. Brairch, AIIMS, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJPC.IJPC_30_18

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The patients often present to palliative care with intractable nausea and vomiting. This may reduce the effectiveness of oral drugs and significantly affects the quality of life of these patients. Despite multiple drugs available for treatment, it is often difficult to control the symptoms. Olanzapine is an atypical antipsychotic and acts on multiple receptors and may help in treating vomiting in a patient with advanced malignancy. We report a case of gallbladder carcinoma who presented to us with intractable vomiting which was not relieved with a combination of traditional antiemetics but showed marked improvement with olanzapine.






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