Indian Journal of Palliative Care
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 REVIEW ARTICLE
Year : 2011  |  Volume : 17  |  Issue : 3  |  Page : 175--183

Pain in blood cancers


1 Department of Hematology, S. Eugenio Hospital, Rome, Italy
2 Department of Radiation and Radiotherapy, University of Rome La Sapienza, Rome, Italy

Correspondence Address:
Pasquale Niscola
Department of Hematology, S. Eugenio Hospital, Rome
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1075.92333

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Patients with blood-related cancers (BRC) suffer from a substantial symptom burden, including several pain syndromes sustained by different causes and pathogenetic mechanisms. So, with regard to pain, a multifaceted clinical scenario may be observed in this setting. Indeed, pain may be correlated to disease itself, to disease-associated complications, to iatrogenic causes or may be due to unrelated clinical conditions. A close diagnostic procedure for the assessment of the underlying causes of the pain and of its pathogenetic mechanisms may direct the treatment approach which should be based on a multidisciplinary management and requires the integration of etiology-targeted interventions and painkilling drugs. The World Health Organization's three-step analgesic ladder for cancer pain relief can provide adequate pain control using oral drugs in most patients with BRC on pain, although more complex interventions may be necessary for many difficult-to-treat pain syndromes which are not infrequently encountered in this setting.






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Online since 1st October '05
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