Indian Journal of Palliative Care
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Year : 2011  |  Volume : 17  |  Issue : 2  |  Page : 92--97

Evaluation and management of fatigue in oncology: A multidimensional approach


Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco

Correspondence Address:
El Mehdi Tazi
Department of Medical Oncology, National Institute of Oncology, Rabat
Morocco
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1075.84528

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Fatigue, one of the most common symptoms experienced by cancer patients, is multidimensional and is associated with significant impairment in functioning and overall quality of life. Although the precise pathophysiology of cancer-related fatigue (CRF) is not well understood, a number of metabolic, cytokine, neurophysiologic, and endocrine changes have been described in these patients. A better understanding of these abnormalities is likely to lead to novel therapeutic interventions. Clinically, all patients presenting with significant fatigue should be evaluated for treatable conditions that might contribute to this symptom. Exercise and treatment of anemia are the two most established interventions for CRF. Psychostimulants seem promising based on early studies. Several complementary medicine treatments that showed efficacy in preliminary studies merit further testing.






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Online since 1st October '05
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