Indian Journal of Palliative Care
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 REVIEW ARTICLE
Year : 2009  |  Volume : 15  |  Issue : 2  |  Page : 95--102

Radiation induced oral mucositis


1 Department of Oral Medicine and Radiology, Government Dental College, Trivandrum, India
2 Department of Radiotherapy, Regional Cancer Center, Trivandrum, India

Correspondence Address:
P S Satheesh Kumar
Department of Oral Medicine and Radiology, Government Dental College, Trivandrum
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1075.58452

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Patients receiving radiotherapy or chemotherapy will receive some degree of oral mucositis The incidence of oral mucositis was especially high in patients: (i) With primary tumors in the oral cavity, oropharynx, or nasopharynx; (ii) who also received concomitant chemotherapy; (iii) who received a total dose over 5,000 cGy; and (iv) who were treated with altered fractionation radiation schedules. Radiation-induced oral mucositis affects the quality of life of the patients and the family concerned. The present day management of oral mucositis is mostly palliative and or supportive care. The newer guidelines are suggesting Palifermin, which is the first active mucositis drug as well as Amifostine, for radiation protection and cryotherapy. The current management should focus more on palliative measures, such as pain management, nutritional support, and maintenance, of good oral hygiene






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Online since 1st October '05
Published by Wolters Kluwer - Medknow